Sacral Neuromodulation for Male Overactive Bladder (MOAB)
About
Overactive bladder (OAB) is a condition characterized by sudden, strong urges to urinate, often accompanied by leakage (urge incontinence). In men who have undergone surgery or radiation for prostate cancer, or procedures for benign prostatic hyperplasia (BPH), OAB is particularly common and can severely disrupt daily activities, sleep, and quality of life. Standard treatments such as medications often provide incomplete relief. Sacral neuromodulation (SNM)—a therapy using mild electrical impulses to regulate bladder nerve activity—offers a proven option but has been understudied in this specific male population.
Purpose
This post-market study assesses real-world clinical outcomes of the Axonics sacral neuromodulation (SNM) system in men with OAB who have a prior history of radical prostatectomy, radiation for prostate cancer, or surgical treatment for BPH. The primary goal is to evaluate improvement in OAB symptoms after SNM therapy. This study aims to generate important evidence on how SNM performs in an underrepresented and clinically challenging male patient population.
Eligibility
- Adult males with overactive bladder symptoms
- Prior history of radical prostatectomy, radiation for prostate cancer, or surgical treatment for BPH
- Inadequate response to conservative OAB treatments such as medications
- No active urinary tract infection or anatomic abnormality contraindicating SNM therapy
Benefits
If you qualify for the study, all study-related medical care and treatment will be provided to you at no cost. You may receive a stipend for your participation in the study.
Send us a message if you are interested in participating in a study.
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